In our recent question and answer, the pharmacist discusses drug and also medications that have been report to reason false positives on medicine tests for marijuana.

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doc asked

I have received a false confident for marijuana from a doctor testing me since I use hydrocodone. However I execute not use it so my medication has been cut off. Ns am in serious pain because that degenerative key disorder in mine spine. I carry out use high sheep of ibuprofen native the exact same doctor. Don"t understand what has actually put me in this position.

Answer

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Many various over the counter and also prescription medications have actually been reported to cause false positives for marijuana (specifically THC metabolites) ~ above urine medicine tests. Research studies have shown that commonly used over the counter medications, such as Advil (ibuprofen), have the potential to reason unexpected results.

MarijuanaDrug check False Positives

Although marijuana contains hundreds of compounds, medicine screenings normally test for the THC metabolite delta-9-tetrahydrocannabinol-9-carboxylic acid. The adhering to medications have actually been report to cause false positives:

NSAIDs (Non-Steroidal Anti-Inflammatory Drugs): commonly used NSAIDs encompass Advil (ibuprofen), Aleve (naproxen), diclofenac, Mobic (meloxicam) and Celebrex. NSAIDs are some of the most often used over the respond to pain medications.Efavirenz: Efavirenz is an anti-retroviral medication provided to treat HIV/AIDS.PPIs (Proton Pump Inhibitors): generally used PPIs include Prilosec (omeprazole), Prevacid (esomeprazole), Zegerid (omeprazole/sodium bicarbonate) and also Protonix (pantoprazole).How drug Tests Work and also False Positives

As drug tests are regularly used in pre-employment screenings and medical settings, there is a demand for straightforward testing methods and fast results. The most frequently used drug tests space urine based immunoassay tests and unfortunately, they space subject come false positives an interpretation they can present a hopeful reading for a drug that is not existing in a sample.

Common immunoassay tests incorporate the EIA (Enzyme connected Immunoassay) test and also the CEDIA (Closed Enzyme Donor Immunoassay) test, which both use similar principles. They work-related by using antibodies to reaction to specific drug compounds.When a drug compound is present in a test sample, one antibody binds to it, i m sorry produces a reaction. When a reaction occurs, the is classified as "positive" result.

Unfortunately, immunoassay based tests have a far-reaching problem with "cross-reactivity", where drugs that space NOT being tested for react v the wrong antibody (i.e. "cross react"), which results in a "false-positive". This may have happened in her case, especially due to the fact that NSAIDs like ibuprofen have actually been shown to it is in responsible for marijuana false-positives.

In fact, one study uncovered that ibuprofen led to a false-positive top top a marijuana drug test in two topics after just one days use of ibuprofen.

If you get an unexpected an outcome on a medicine test, the is important to inquire about the possibility of a an ext accurate, confirmatory check that can actually identify specific molecules and don"t use antibodies. Such tests include gas or liquid chromatography v mass spectrometry.

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Additional Information

In those that perform use marijuana, detection times vary widely through individual and also usage history. One time use of marijuana can typically be detected for 3 to 7 days on pee tests while continual use can lead to an individual testing positive for over 30 job after last use.