Main distinction – Synapsis vs crossing Over

Synapsis and crossing over room two events that occur during the chromosome distinction in meiosis 1. Meiosis occurs during the production of gametes in order to attain the sexual reproduction that organisms. Both synapsis and crossing end are crucial in exerting genetic variation among the people by enabling the exchange of genetic material between homologous chromosomes. The main difference in between synapsis and also crossing over is the synapsis is the pairing the homologous chromosomes throughout the prophase 1 that the meiosis 1 whereas crossing end is the exchange of the hereditary material during synapsis.

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1. What is Synapsis – Definition, Mechanism, Function, Characteristics 2. What is cross Over – Definition, Mechanism, Function, Characteristics 3. What is the difference in between Synapsis and Crossing Over


What is Synapsis

The pairing that the two homologous chromosomes throughout the meiosis is well-known as synapsis. The synapsis occurs at prophase 1 the meiosis 1. It enables the 2 homologous chromosomes to segregate in ~ the anaphase 1 that meiosis 1.

Mechanism the Synapsis

During synapsis, the ends of the separation, personal, instance chromosomes room attached come the atom envelope first. This chromosomal end-membrane complexes are moved until they discover the other homologue come pair through the aid of the extranuclear cytoskeleton. Then, the intervening areas of the two chromosomes are associated by synaptonemal complexes, i beg your pardon consist that RNA and proteins. A synaptonemal complicated is presented in figure 1.


Figure 1: Synaptonemal complicated (SC)(A) Lateral view: homologous chromosomes (light blue rods) aligned together by the meshwork of transverse (black lines) and longitudinal (dark blue rods) filaments. (B) Tomato SCs in ~ the top and also two tomato SCs (Crossing end occurs in ~ the marked sites.)

Autosomes form two synaptonemal complexes at the two ends that the chromosome. But, sex chromosomes type a solitary synaptonemal complicated at one end of every chromosome.

Function of Synapsis

The significant role that synapsis is the recognition of the 2 homologues through pairing, in bespeak to experience a successful synapsis. Throughout synapsis, genetic variation is permitted in two ways. First is the independent orientation that the bag of the homologous chromosomes in the cabinet equator. This is called the law of live independence assortment, which enables the segregation of maternal and paternal chromosomes in a arbitrarily nature. Secondly, the chromosomal cross-over at chiasmata the non-sister chromatids enables the hereditary recombination of chromosomes to occur, resulting in brand-new combinations that alleles in the inherited chromosomes. DNA repair wake up in response to DNA damage, particularly double-strand breaks during synapsis.

What is cross Over

The exchange the DNA pieces in between non-sister chromatids during the synapsis is well-known as cross over. Thus, chromosomal crossing end occurs during the prophase 1 the meiosis 1 in the sexual reproduction.

Mechanism of crossing Over

Crossing over occurs as soon as breaking down of comparable DNA regions occurs in ~ the homologous chromosome pair, resulting in the genetic recombination. Non-sister chromatids in this corresponding DNA regions intertwine first, break apart the similar DNA regions. This comparable DNA areas are exchanged v crossing over. The chiasma is an X like region, where the two non-sister chromatids are joined together throughout crossing over. The development of the chiasma stabilizes the bivalents or the chromosomes during their distinction at the metaphase 1. The procedure of crossing end is shown in figure 2.


Figure 2: crossing Over

Synthesis-dependent strand annealing (SDSA) is another kind of recombination the occurs throughout synapsis, which enables the exchange that information, yet not the physical exchange of DNA pieces.

Function of cross Over

Crossing over increases the hereditary variation within an offspring. The hereditary variation exerted by cross over provides a defense versus the procedure called chromosome killer. The repeated crossing over enables the genes in that regions to concentrate independently. The concentration of advantageous genes would certainly be an benefit towards the species.

Difference between Synapsis and also Crossing Over


Synapsis: The pairing that the homologous chromosomes throughout the prophase 1 that the meiosis 1 is recognized as the synapsis.

Crossing Over: The exchange of the genetic material throughout synapsis is recognized as the crossing over.


Synapsis: Synapsis wake up at first.

Crossing Over: Synapsis is complied with by cross over.


Synapsis: Synapsis constantly occurs.

Crossing Over: Crossing over may take place sometimes.


Synapsis: Synapsis ensures the suitable segregation of homologous chromosomes and enables the recombination with crossing over.

Crossing Over: crossing over enables the sports of alleles in a populace through genetic recombination.


Synapsis: two homologous chromosomes come together during synapsis.

Crossing Over: DNA pieces of the non-sister chromatids space exchanged during crossing over.

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Synapsis and crossing over occurs during the prophase 1 of meiosis 1, i m sorry is involved in the sex-related reproduction of organisms. Synapsis is the pairing that homologous chromosomes in a cell. The 2 chromosomes are hosted together by synaptonemal complexes, i beg your pardon are formed by a arsenal of RNA with proteins. Chiasma is the position where the two non-sister chromatids are organized together during synapsis. The is an X-shaped DNA region, which allows the double-strand break of both non-sister chromatids, trading the hereditary material in between the 2 non-sister chromatids. This form of exchanges in genetic material are recognized as recombination. Hereditary variation is do up amongst the offspring through recombination. The main difference between synapsis and also crossing end is their correspondence in addition to the function.

Reference: 1. “Synapsis.” Wikipedia. Wikimedia Foundation, 18 Feb. 2017. Web. 15 Mar. 2017. 2. “Chromosomal crossover.” Wikipedia. Wikimedia Foundation, 13 Mar. 2017. Web. 15 Mar. 2017.

Image Courtesy:1. “Synaptonemal complex” through Images and also legend courtesy that Daniel G. Peterson, Mississippi Genome exploration Laboratory, Mississippi State University, Mississippi State, Mississippi, united States. (CC through 2.5) via Commons Wikimedia2. “Cross-over” (Public Domain) via Commons Wikimedia