Doctors prescribe prazosin come treat high blood pressure. However, it has actually been prescribed “off-label” for various problems not authorized by the U.S. Food and Drug management (FDA) including an enlarged prostate, congestive love failure, Raynaud’s disease, and most notably, the sleep-related problems connected with post-traumatic stress and anxiety disorder (PTSD).

In fact, prazosin has even been prescribed to treat scorpion stings. 

As with any drug, even if it is prescription or illicit, prazosin can produce psychotropic results when abused. Its usage can reason uncomfortable next effects, from lightheadedness and vomiting come fainting and also depression.

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Unlike benzodiazepines or alcohol, prazosin overdose is not life-threatening.

Still, the recreational usage of prazosin have the right to be dangerous. Review on to learn much more about this medication and also the steps you have the right to take to rest dependence and addiction.

What is Prazosin?

The alarming pervasiveness of high blood press in the U.S. Provides medication a necessity for many, together 1 in 3 U.S. Adults (about 75 million) have actually the condition. That’s why alpha-blocker drugs such as prazosin have actually such value.

Prazosin functions by be sure the blood vessels, which enables the blood to flow an ext easily through the body. It deserve to be administered by itself to treat high blood pressure or in mix with diuretic or beta-blocker medications. Prazosin, which comes as a tablet or capsule, is offered under the brand surname of Minipress and also is easily accessible in share form.

A popular, “off-label” use for prazosin is to treat the sleep disorders that come v PTSD, a problem that reasons people come relive traumatic incidents and also suffer nightmares from occasions they have actually experienced or witnessed.

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“Off-label” means the drug has not obtained FDA approval to treat PTSD, yet doctors have the right to legally prescribe the or any type of treatment so lengthy as it meets a patient’s needs. Those more, the U.S. Department of Veterans Affairs and the American Psychiatric association (APA) have stated that prazosin is reliable in dealing with the nightmares proficient by armed forces combat personnel. 

A tiny study suggested, however, that prazosin might make nightmares and also insomnia associated with PTSD worse. It additionally found that the drug might not mitigate suicidal thoughts in patients who have PTSD.

What’s more, prazosin can create effects that make recreational use dangerous. 

Why is entertain Prazosin usage Dangerous?

Prazosin use isn’t life-threatening in the means that much more potent substances prefer opioids and also stimulants are. However, it is capable of producing concerning effects. For one, upon an initial use, prazosin can cause someone to experience dizziness, lightheadedness, and also fainting if they obtain up too easily from a lie down position after taking the medication.

Also, prazosin deserve to make users drowsy come the point where driving a auto or operating machinery i do not care a attention endeavor.

Plus, the usage of this medication can cause troubling side effects, both common and also not-so-common. Usual side effects associated with prazosin include: 

TirednessNauseaHeadacheWeaknessLow blood pressure

The serious, not-so-common side results can include:

RashHivesItchingRapid or rarely often rare heartbeatDifficulty breathingChest painPainful, lengthy erection in men

Prazosin does no pose the seeks potential of sedative medications such as zolpidem (Ambien), temazepam (Restoril), and zaleplon (Sonata). Still, if sufficient of this medication is taken, it can create a psychotropic effect. That result is enough to reason users to exceed their dosage to chase the effect that a previous dose yielded.

What’s more, any type of substance can develop dependence in a user, i m sorry the national Institute on drug Abuse (NIDA) defines as a state in which the body only attributes normally when a problem is present. Tolerance and dependence have the right to quickly decrease into addiction when someone exhibits compulsive habits in search the drug. Prazosin is no different.

According to the Diagnostic and Statistical hands-on of psychological Disorders, fifth Edition (DSM-5), there room 11 criteria for drug addiction that assist clinicians diagnose seeks disorders. If someone shows at the very least two of these symptoms end 12 months, they may have a substance use disorder:

Taking more of the drug 보다 intended, because that a longer duration than intendedA persistent desire to prevent taking drugs or repeated unsuccessful attempts come quit acquisition drugsA the majority of time spent trying to obtain drugs, abuse them, and/or recover from their effectsIntense cravings or urges for particular drugsFailing to go to job-related or school, or to satisfy obligations come friends and also family due to the fact that of drug abuseOngoing drug abuse regardless of the physical, mental, emotional, or social problems associated with the abuseGiving increase hobbies or activities to abuse drugsOngoing abuse of medicine in unreasonable situations, choose using them in the morning before work, driving while intoxicated, or abusing drugs approximately childrenExperiencing physics or psychological difficulties due to substance abuse yet continuing to abuse drugs anywayPhysical tolerance, definition the body needs an ext of the drug to suffer the original level that intoxicationExperiencing symptom of withdrawal when trying to quit the drug

If you have actually been prescribed Minipress or share prazosin and also have exhibited any type of of the abovementioned addiction symptoms, then it is imperative the you seek expert addiction treatment. This is particularly true if you have actually abused prazosin with alcohol and other drugs.

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What is involved in Prazosin seeks Treatment?

A substance choose prazosin is not addictive when compared to opioids and benzodiazepines. Thus, addiction may not call for the much more intensive level of care that are the cornerstones of expert treatment.

However, if you space abusing prazosin with alcohol or other drugs, the after-effects can be much more pronounced, if no life-threatening. In those cases, the most effective treatment plan will require clinical detoxification and also residential treatment. In detox, the substances will certainly be removed from your system while any type of withdrawal symptoms, effects, or medical concerns are addressed and also alleviated.


Residential treatment will offer you ongoing treatment at a treatment facility, where you will certainly live for a certain period. In ~ this level, you will obtain therapy and counseling that help you get to the root of her addiction. In instances of polysubstance abuse, a 90-day remain in residential treatment is recommended.

Because prazosin is a psychotropic addiction, that is still qualified of creating psychological addiction. That’s why outpatient treatment via an extensive outpatient (IOP) or partial hospitalization (PHP) routine is an effective solution.

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Any of this tracts will enable you access to evidence-based therapies while providing you the freedom and also flexibility to deal with your life obligations. Ultimately, expert treatment is your safest method of preventing the after-effects that come through recreational prazosin use.



Written by: Tacuma Roeback

Kowalski, J. (2018, December 03). Guide to drug Addiction: Symptoms, Signs, and Treatment. Retrieved native academy on medicine Abuse. (n.d.). 8: an interpretation of dependence. Retrieved indigenous (Minipress) – side Effects, Dosage, interactions – Drugs. (2014, September 25). Retrieved from for post-traumatic tension disorder. (n.d.). Retrieved from oral : Uses, next Effects, Interactions, Pictures, Warnings & Dosing. (n.d.). Retrieved indigenous MedlinePlus drug Information. (n.d.). Retrieved from, R. (2018, December 27). PTSD Drug might Do much more Harm Than great – WebMD. Retrieved native 7 Sources